The CEO is Dr. Mark Lemstra. Academically, Mark has completed nine university degrees including a doctor of science in clinical epidemiology, a doctor of science in public health, a PhD in epidemiology and a PhD in psychiatry. Previously, Mark was the coordinator of behavioral medicine at academic family medicine, and an adjunct professor in pediatrics and psychiatry, at the College of Medicine at the University of Saskatchewan.

The medical director at Alliance Health medical clinic in Moose Jaw is Dr. Brad Thorpe. He is a Clinical Assistant Professor in the College of Medicine at the University of Saskatchewan and is a preceptor for new family medicine residents. Dr. Thorpe is the Head of Department of Family Practice in the Five Hills Health Region and is President of the Regional Medical Association. Other family physicians include: Dr Jamie Stushnoff, Dr. Mark Voogt, Dr. Joanne Fynn, Dr. Heather Konkin, Dr. Rob Haver, Dr. Brent Janzen, Dr. Andrea Martin  and Dr. Samme Henley. The Moose Jaw clinic also includes: Dr. Jason Shin (orthopaedic surgeon) and Dr. Wale Afolabi (psychiatrist).

The medical director at Alliance Health medical clinic in Regina is Dr. N Parwez. Other family physicians include: Dr. Afam Nwalusi, Dr. Hope Anigboro, Dr. Naseer Firdosi and Dr. Lane Rathgeber. The Regina clinic also includes: Dr. Moustfha Alshrif (orthopedic surgeon), Dr. Hakim Raghig (neurologist), Dr. Mike Nicholls (sports medicine), Dr. Akbar Alavudeen (inernist) and Dr. Mike Roy (cardiologist).

The family physicians at Alliance Health medical clinic in Saskatoon include: Dr. K Shukla, Dr. S Shukla and Dr. N Firdosi. The Saskatoon clinic also includes: Dr. Ruphus Rajakumar (general surgeon), Dr. Sarah Tehseen (pediatrician), Dr. Peter Gregor (cardiologist), Dr. W Janss (internist), Dr. A Masood (psychiatrist), Dr. R Safavi (psychiatrist) and Dr. Lorne Weeks (orthopedic surgeon).